Antiseptic vs. Antibacterial Mouthwash: Which Should You Use?

Both antiseptic and antibacterial mouthwashes can help to keep your mouth healthy when used as part of a full oral hygiene routine. Your particular dental needs can dictate which type of mouthwash will be ideal for you.

These are key differences between antiseptic vs. antibacterial mouthwashes:

Sources: National Institutes of Health, International Dental Journal

Understand key dental terms

What should you look for when shopping for mouthwash? What terms are important to you as you browse the aisles? Learning more about labels and typical terminology may help.

Common terms you may see while shopping for dental mouthwash include the following:

• Antimicrobial: A substance that kills things like bacteria or mold

• Antibacterial: A substance that kills bacteria

• Antiseptic: A substance that slows or stops microorganisms from growing, which could prevent an infection

Antiseptic Mouthwash

Antiseptic mouthwashes can help to control plaque from building up by disrupting the bacterial load in your mouth.

Prescription antiseptic mouthwashes often contain chlorhexidine (CHX), which has antimicrobial effects and is often used to treat gingivitis.¹ CHX can lead to tooth staining and disrupt the natural balance of your mouth, however. When prescribed, it is generally to be used on a short-term basis.

Additional antiseptic mouthwashes can contain the following active ingredients, which can help to control plaque buildup, gum disease, and also bad breath:

• Hydrogen peroxide

• Menthol

• Eucalyptol

• Sodium chloride

• Fluoride

Here are some popular brands of antiseptic mouthwash:

• Listerine Cool Mint Antiseptic Mouthwash

• Equate Antiseptic Mouthwash

• Orajel for All Mouth Sores Antiseptic Rinse

• ACT Total Care Anticavity Mouthwash

• Colgate Peroxyl Antiseptic Mouthwash and Mouth Sore Rinse

Antibacterial Mouthwash

Antibacterial mouthwashes are like antibiotics in that they target specific bacteria and can be used when there is an active infection.² They can help to keep plaque from building up and often contain active antibacterial ingredients, such as cetylpyridinium chloride.³

There are both over-the-counter and prescription-based antibacterial mouthwashes. Here are some examples:

• Crest Pro-Health Intense Clean Mint Mouthwash

• Colgate Total Advanced Pro-Shield Mouthwash

• TheraBreath Fresh Breath Dentist Formulated 24-Hour Oral Rinse

• CloSYS Sensitive Antimicrobial Mouthwash

Antibacterial mouthwashes can cause side effects like mouth irritation or tooth staining.

How to choose a mouthwash

With so many different types of mouthwashes available, how can you choose the right one? Start with your dentist. Ask about your oral health and how a mouthwash might help. In some cases, your doctor will prescribe a solution. In others, you can purchase a product that seems just right.

If you need an over-the-counter mouthwash, look for products that are marked with the American Dental Association (ADA) Seal of Approval. These products contain ingredients the ADA says are safe and effective.

Best mouthwash for infected gums

Those suffering with gum problems or gum disease (including early-stage gingivitis) should look for mouthwashes that are targeted for gum health. Different formulations use different ingredients, including cetylpyridinium chloride, chlorhexidine, and essential oils.

These are some top-rated mouthwashes for gum health:

• Colgate Total Gum Health Mouthwash: This alcohol-free formula has a “clean mint” flavor and antiseptic properties.

• Dental Herb Company Tooth & Gums Tonic: This anti-inflammatory mouthwash costs more than most other options, but it receives top reviews for its unique herbal and essential oil blend.

• Listerine Gum Therapy Antiseptic Mouthwash: Listerine claims this fluoride anticavity mouthwash will reduce symptoms of gum disease, including redness, bleeding, and inflammation.

Medicated mouthwash

When referring to medicated mouthwash, there are both prescription mouthwashes (which must be prescribed or provided by a doctor or dental professional) and specialized, therapeutic mouthwashes that are available to consumers to target certain conditions.

Prescription medicated mouthwashes

If needed, your dentist will recommend a prescription medicated mouthwash for certain oral health problems like gum disease or mouth sores. You can also ask your dentist about prescription mouthwash if you feel it would be helpful.

Common prescription medicated mouthwashes include the following:

• Chlorhexidine: This is a popular mouth rinse used to treat gingivitis.

• Magic mouthwash: This is a pain-relieving mouthwash formula to ease the discomfort of mouth sores. It is often used by chemotherapy patients.

• Colgate Prevident Dental Rinse: This is a fluoride mouthwash designed to prevent cavities and decay for those who have trouble brushing.

Non-prescription medicated mouthwashes

Some mouthwashes offer a higher-strength or custom formula to treat certain conditions. These are also known as over-the-counter medicated mouthwashes and include the following:

• Parodontax Active Gum Health Mouthwash: This is an alcohol and fluoride-free formula using cetylpyridinium chloride (CPC).

• Oral B Mouth Sore Oral Rinse: Paraben- and alcohol-free, this mouthwash uses hydrogen peroxide as its active ingredient and features a soothing mint flavor.

• Orajel for Toothache Mouthwash: This is a pain-relieving mouth rinse that can be used up to four times a day to relieve toothache pain.

Antiseptic & Antibacterial Mouthwash Frequently Asked Questions